BDBM14775 3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide::3-cyclopentyloxy-N-(3,5-dichloropyridin-4-yl)-4-methoxy-benzamide::CHEMBL42126::Cpodpmb::Piclamilast::RPR-73401
SMILES COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(Cl)cncc1Cl
InChI Key InChIKey=RRRUXBQSQLKHEL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 14775
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
University of Tennessee
Curated by PDSP Ki Database
University of Tennessee
Curated by PDSP Ki Database
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
University of Tennessee
Curated by PDSP Ki Database
University of Tennessee
Curated by PDSP Ki Database
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human Phosphodiesterase 4BMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of human His-tagged PDE4B catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of human His-tagged PDE4B catalytic domain expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP or [3H]cGMP as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0410nMAssay Description:Inhibition of human PDE4B by scintillation counting methodMore data for this Ligand-Target Pair